Doctoral Theses

Descubrimiento y optimización de nuevos agentes antitumorales empleando reacciones multicomponente

Multicomponent Strategies for GPCR Targeting: Allosteric Modulation of Dopamine Receptor D2 and Development of Potent and Selective CB2R Agonists

A2B Adenosine Receptor as a Novel Target in Cancer Immunotherapy: Validation and Optimization of New Ligands

Discovery and Optimization of Selective CB2 Receptor Agonists

New Ligands and Pharmacological Tools for The Study of G Protein coupled Receptors Using Multicomponent Reactions

Investigation on Biosisoteric Replacement in Lead Optimization of Novel Pharmacological Agents in Cancer and Other Major Therapeutic Areas

Multicomponent Approaches to Assembly Heterocyclic Chemotypes Dual Targeting Adenosine Receptors and Phosphodiesterases

Synthesis and Applications of Novel Polymeric-Based Heterogeneous Catalytic Systems.

Novel Multicomponent Approaches to Accelerate the Identification and Optimization of Pyrimidine Derivatives as Potent and Selective A3 Antagonists.

New Applications of Ugi Reaction in Drug Discovery.

Multicomponent Approaches in Drug Discovery: Identification and Optimization of Potent and Selective A2B Antagonists Using the Biginelli Reaction.

Synthesis and Biological Evaluation of Pyridazin-3-one-Chalcone Hybrid Structures as Platelet Aggregation Inhibitors.

Pyridazin-3-one-Based Antiplatelet Agents: Optimization and Structural Diversification of 2,5-Substituted Pyridazin-3-ones Using Palladium-Catalysed Reactions.