Doctoral Theses

2023

A2B Adenosine Receptor as a Novel Target in Cancer Immunotherapy: Validation and Optimization of New Ligands

Discovery and Optimization of Selective CB2 Receptor Agonists

2021

New Ligands and Pharmacological Tools for The Study of G Protein coupled Receptors Using Multicomponent Reactions

2018

Investigation on Biosisoteric Replacement in Lead Optimization of Novel Pharmacological Agents in Cancer and Other Major Therapeutic Areas.

2016

Multicomponent Approaches to Assembly Heterocyclic Chemotypes Dual Targeting Adenosine Receptors and Phosphodiesterases

2016

Synthesis and Applications of Novel Polymeric-Based Heterogeneous Catalytic Systems.

2013

Novel Multicomponent Approaches to Accelerate the Identification and Optimization of Pyrimidine Derivatives as Potent and Selective A3 Antagonists.

2013

New Applications of Ugi Reaction in Drug Discovery.

2012

Multicomponent Approaches in Drug Discovery: Identification and Optimization of Potent and Selective A2B Antagonists Using the Biginelli Reaction.

2009

Synthesis and Biological Evaluation of Pyridazin-3-one-Chalcone Hybrid Structures as Platelet Aggregation Inhibitors.

2003

Pyridazin-3-one-Based Antiplatelet Agents: Optimization and Structural Diversification of 2,5-Substituted Pyridazin-3-ones Using Palladium-Catalysed Reactions.

A2B Adenosine Receptor as a Novel Target in Cancer Immunotherapy: Validation and Optimization of New Ligands