Potent and Subtype-Selective Dopamine D2 Receptor Biased Partial Agonists Discovered via an Ugi-Based Approach

Ana Mallo-Abreu, Irene Reyes-Resina, Jhonny Azuaje, Rafael Franco, Aitor García-Rey, Maria Majellaro, Darío Miranda-Pastoriza, Xerardo García-Mera, Willem Jespers, Hugo Gutiérrez-de-Terán,
Gemma Navarro, and Eddy Sotelo*

 

J. Med. Chem. 2021, 64, 8710-8726

https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c00704