Nitrogen-Walk Approach to Explore Bioisosteric Replacements in a Series of Potent A2B Adenosine Receptor Antagonists

Nitrogen-Walk Approach to Explore Bioisosteric Replacements in a Series of Potent A2B Adenosine Receptor Antagonists

Ana Mallo-AbreuRubén Prieto-DíazWillem JespersJhonny AzuajeMaria MajellaroCarmen VelandoXerardo García-MeraOlga CaamañoJosé BreaMaría I. LozaHugo Gutiérrez-de-Terán, and Eddy Sotelo

 

Journal of Medicinal Chemistry, 2020, 63, 7721-7739.

 

https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00564